Symantec Endpoint Protection Manager (SEPM) installation is corrupted and it needs to be reinstalled and connected to existing SQL database. Symptoms indicating a corrupted SEPM install include but are not limited to: SEPM failure to deploy content/definitions to the clients.
To resolve the error, temporarily unmap the drive mentioned in the error and reattempt the uninstall / reinstall . The mapping can be safely recreated afterwards. If the attempt continues to fail, and re-establishing the mapped drive has not affect, follow the steps outline in the following technote to manually uninstall the product before any reinstall attempt: www.symantec.com/docs/tech55097