The following vbscript is a concise example of how to determine if a Windows machine has a wow6432node in its registry: 

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' Determine if computer is x64 by the existence of the HKLM\SOFTWARE\Wow6432Node registry key

Const HKLM = &H80000002
Dim strRootKeyPath, arrSubKeys

Set objRegistry=GetObject("winmgmts:{impersonationLevel=impersonate}!\\.\root\default:StdRegProv")
strRootKeyPath = "SOFTWARE\Wow6432Node"
objRegistry.EnumKey HKLM, strRootKeyPath, arrSubKeys

if IsNull(arrSubKeys) Then
strAdobePath = "SOFTWARE"
Wscript.echo "empty"
else
strAdobePath = "SOFTWARE\Wow6432Node"
Wscript.echo "not empty"
End If 

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