No, the Symantec AntiVirus Corporate Edition/Symantec Endpoint Protection scan engine cannot open MS SQL database files because they are in a proprietary file format. This behavior is working as designed by Microsoft.

You can, however, install Symantec AntiVirus or Symantect Endpoint Protection onto a MS SQL server to protect the operating environment and file system.

When you install Symantec AntiVirus/Symantec Endpoint Protection onto a MS SQL server, you may need to configure it to exclude the MS SQL database files from real-time (Auto-Protect) and manual or scheduled scans.



References
For detailed instructions on how to set up exclusions, please see the following articles::

SAV: Excluding specific drives and folders from Symantec AntiVirus scans

SEP: How to exclude SQL files and folders using Centralized Exceptions

Microsoft's document on this topic:

Guidelines for choosing antivirus software to run on the computers that are running SQL Server (http://support.microsoft.com/kb/309422/)