The Symantec Protection Engine (SPE) is NOT AFFECTED by this vulnerability, as it does not use the TLS / DTLS functionality from OpenSSL; however, an optional patch is offered in this document, simply to exclude the specific OpenSSL version (1.0.1e) from the build. This patch is built with OpenSSL 1.0.1g, and after its application the product build number is SPE 220.127.116.11 (HF03).
This proactive patch is purely OPTIONAL. SPE 18.104.22.168 is NOT AFFECTED by the HeartBleed vulnerability without this patch.
Previous Hotfix (HF02) was withdrawn to also update the OpenSSL components for the other SPE's auxiliary components such as Titanium, Lux, and Defutils (described in the ReadMe). If you have already applied HF02 (SPE22.214.171.124), that can be safely overwritten by this HF03, or you can directly update from SPE 126.96.36.199 (no patch). Note that both HF02 and HF03 are OPTIONAL and SPE IS NOT AFFECTED by the CVE-2014-0160 vulnerability without HF02/HF03.