Some applications generates missing library files when launching on 32bit application.
Applications that require a depended application or layer that supplies the dlls for the application to run can cause some "Unable to locate file" issues due to the dll not being able to be located in the dependent layer. The 6.x version of streaming was designed around legacy windows operating systems and its functionality has changed in 7.x to change with modern windows operating systems.
There is currently no solution for this issue.
A procmon will have to be captured to see where exactly the application is looking for the missing dll. Then edit the layer and copy that dll into that location so that the application is able to locate the file.