In some cases, we get an "Open With" box while accessing any executable. This problem occurs if the .exe file association in the registry is corrupt. This behavior is generally caused by viruses. Click Start, Run and type "regedit" If Registry Editor opens successfully, then navigate to the following key: HKEY_CLASSES_ROOT \ exefile \ shell \ open \ command Double-click the (Default) value in the right pane Delete the current value data, and then type: "%1" %* (ie., quote-percent-one-quote-space-percent-asterisk.) Navigate to: HKEY_CLASSES_ROOT\.exe In the right-pane, set (default) to exefile Exit the Registry Editor. If registry editor does not open, then follow the steps below: Open Explorer Go to Tools->Folder Options ->File Types Click on New Provide the File Extension as "EXE" click on Advanced In the drop down menu " Associated File Type", choose "Application" Click on OK.