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I had the same error Natwhite01.
After removing the “Automatically uninstall existing Security Software” from the client install settings I exported a new package. The installation got further along but still failed. The following was in the SEP_INST.LOG “Product: Symantec Endpoint Protection -- Error 25100. The Symantec Endpoint Protection installation could not finish because Windows could not verify a DLL signature”
The solution to both seems to be update the root certificates. Refer to this Symantec Tech article: http://www.symantec.com/docs/TECH217284
Perhaps Symantec can explain why this is necessary as the release notes for SEP12.1 RU5 and the above mentioned tech article claims that with 12.1.5, the installation automatically installs the required certificates.
Since upgrading to 12.1 RU5 we get this error with some of the installations when exporting the client and running the .exe
I'm not sure why this error is even appearing as we don't use any other AV products than SEP.