SEP 12.1 RU1 is now available on FileConnect. You will need to use your SEP 12.1 M# (serial) to login to Fileconnect and access the latest release.
There have been a few changes, such as the inclusion of the Symantec Installation Manager (Altiris platform) that provides access to IT Analytics. SPC 2.0 is the same as before. There is also the inclusion of a separate Mac client. The "Full" download from before was also a bit confusing so it has been renamed to Part1_Installation_EN. You will want to download both Part 1 and 2 so you have all the bits you need.
Last but not least, the SEP Recovery Tool 2.0.24 has been added for easy access.
Release Notes for Symantec™ Endpoint Protection, Symantec Endpoint Protection Small Business Edition, and Symantec Network Access Control, version 12.1 Release Update 1