Thank you for the quick response and for the link Brian81.

Yes, SEP 12.1 64 bit support

use the latest version  SEP 12.1 client , which  can be used to deploy on 64 bit Servers.

In the Installation package under Admin --> tab ( in SEPM) you can find the install package for 32 bit and 64 bit, use this link to create a package and install

http://www.symantec.com/business/support/index?page=content&id=HOWTO59431

You can auto upgrade 32 bit to 64 bit

You can assign a 32-bit and 64-bit package to the same group when you do an auto-upgrade and both clients will automatically upgrade. You don't have to create separate groups for 32-bit and 64-bit clients

Hello,

I agree with Brian, Both Symantec Endpoint Protection Manager and Symantec Endpoint Protection client version 12.1.1000.157 will work with Server 2008 64 bit version.

http://www.symantec.com/docs/TECH163806

Also, all Features of SEP are supported on 64 bit OS

1. AV                                                                  
2. Proactive threat Scan (a.k.a truscan or Sonar)     
3. Bloodhound                                                     
4. Malheur                                                           
5. Tamper Protection                                            
6. Internet email scanning
7. Device Control
8. Firewall
9. IPS
10. Application learning
11. Host Integrity (SNAC)

Reference: Difference between sep 11 AND sep 12.1

https://www-secure.symantec.com/connect/articles/few-feature-differences-between-sep-11x-and-sep-121

Hope that helps!!

Hi

Yes you can install o 64bit system OS

Regards

So is there any difference in installing 32 bit SEP on 64 bit server versus installing 64 bit SEP into 64 bit client ?

32bit on 64bit won't be optimmized for 64bit performance so you'll lose some benefit

Thanks to everyone for all the input. Everyone has contributed to the answer I was looking for.