We've opened a support ticket with Symantec on this. Ticket is still open as of 12/31/12.
As mentioned above, issue is on Dell Latitude D620, D630 and HP EliteBook 8470p -- but not all of them. We have thousands of these machines deployed but only 3 have reported this issue.
We created a hardware customized client with the following settings -- basically it is enabling all 4 options in the custom settings (USB 2.0, IRQ Poll, USB Handoff and Module Load):
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[Section for index 30]
Manufacturer=Hewlett-Packard
Model=HP EliteBook 8470p
KernelParams=root=/dev/ram loglevel=1 need_EHCI irqpoll ge_modinfo=2 USBhandoff
InstallerOpt=
[Section for index 31]
Manufacturer=Dell Inc.
Model=Latitude D620
KernelParams=root=/dev/ram loglevel=1 need_EHCI irqpoll ge_modinfo=2 USBhandoff
InstallerOpt=
[Section for index 32]
Manufacturer=Dell Inc.
Model=Latitude D630
KernelParams=root=/dev/ram loglevel=1 need_EHCI irqpoll ge_modinfo=2 USBhandoff
InstallerOpt=
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Regards,
Roland Thomas