Hi,
This issue can be caused by a conflict with port 8443
To correct the port conflict, follow the steps below on the SEPM server:
Click Start > Program Files > Symantec Endpoint Protection Manager
Run the Management Server Configuration Wizard
Select Reconfigure the management server
Click Next
Change the Server port to an unused port, for example, 8444 may be unused
Continue through the remaining reconfiguration steps and re-enter the password for Database server.
When the Management Server Configuration Wizard has completed, restart the Symantec Endpoint Protection Manager service.