Hello,
Check these Articles which may assist you -
How to configure Application Control in Symantec Endpoint Protection 11.0 : Configuring Application Control Policies
http://www.symantec.com/docs/TECH102525
How to use Symantec Endpoint Protection to block or log legitimate but unauthorized software usage
http://www.symantec.com/docs/TECH97618
Secondly, Another way of doing it is using "system lockdown" to enable\disable applications; check this Article:
How to configure System Lockdown in Symantec Endpoint Protection 11.0
http://www.symantec.com/docs/TECH102526
Hope that helps!!