Hello,
I highly appreciate you uploading the screenshots.
Upon checking the Screenshots, I found few things quickly.
Plan of Action:
Concentrating on the above Screenshot,
Antivirus Engine off - 3 machines, Auto-protect off - 7, Tamper Protection off -1. For these machines, please uninstall SEP client and reinstall them back again.
Restart required - 21, for these clients please restart the machine and run a full scan again.
Concentrating on the above Screenshot,
Majority of the Threats found on the Network are Trojan.Gen.2 which is a Generic Threat.
I would highly appreciate, if you could Message me the Risk Logs from the Symantec Endpoint Protection Manager.
I would also recommend you to follow the following steps:
1) Edit Antivirus and Antispyware policy > Windows Settings > Quarantine > General, under "When New Virus Definitions Arrive" choose "Do nothing".
2) Make sure you have the Latest Microsoft Security Patches updated on ALL the machines.
I would be looking forward for the same.