Yes, it's supported.
System Requirements for Symantec Endpoint Protection, Enterprise and Small Business Editions, and Network Access Control 22.214.171.124.
Microsoft SQL Server 2008 R2 Support for Symantec Endpoint Protection Manager (SEPM) 11.x and 12.1
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What product do you have use ?
SEPM it's supported.
Symantec Endpoint management (Altiris) not supported.
The following applies to Client Management Suite and Server Management Suite. Asset Management Suite does not have an agent.
Great, Thank you!
We are upgrading our Windows server 2003 to 2008, but just wanted to make sure the Symantec database would run on the 2008 servers. We are using Endpoint protection version 12.1.
Yup, you're all set. The link I posted gives all the requirements