Hello,
Why do you want to remove the Samsvc.exe via Symantec Endpoint Protection 12.1 RU5?
Is this file suspicious or malicious?
If yes, submit the file to Symantec Security Response for examination, after the computer upon which they are found has been isolated. Some good articles:
Best Practices for Troubleshooting Viruses on a Network
http://www.symantec.com/docs/TECH122466
Scanning a file with a competitor's antivirus program detects a virus, but scanning with Symantec Endpoint Protection does not
http://www.symantec.com/docs/TECH98929
How to Use the Web Submission Process to Submit Suspicious Files
http://www.symantec.com/docs/TECH102419
What to do when you suspect that a Symantec AntiVirus product is not detecting viruses
http://www.symantec.com/business/support/index?page=content&id=TECH99222
Hope that helps!!