Endpoint Protection

The C drive on a server is filled because the server was designated to store program files and all other data on the D drive.

The All Users exist on C:\ and when SEP client downloads new defintions it is placed in the following location:

C:\Documents and Settings\All Users\Application Data\Symantec\Symantec Endpoint Protection

How do I change the destination location for virus defintions [above location] to a location on the D drive?

Thanks!

You cannot do this. It is hardcoded in SEP. See similar threads:

https://www-secure.symantec.com/connect/forums/change-definition-folder-directory

https://www-secure.symantec.com/connect/forums/moving-sep-121-virus-definition-location

https://www-secure.symantec.com/connect/forums/virus-definition-location-0

its by design, there is enhancement asked for IDEAS section i believe.

You can vote for this feature on the symantec Ideas section under  the below link:

https://www-secure.symantec.com/connect/ideas/change-sep-virus-defination-location

It's not possible "yet".... maybe they will consider this in new version..

Can always vote in Ideas section..

I've wondered about this myself from time to time.

Assuming SEP is following Windows' "Specal Folders" locations, if you were to build a new Windows installation by using the "FolderLocations" settings in an unattend file, SEP's content should follow the %ALLUSERSPROFILE% to the alternative drive.
http://support.microsoft.com/kb/949977

Alternatively, you could also try using the Windows junction function so you could move the defs to another drive, but make Windows (and SEP) think its still in its original location.

I must stress, I've not tried these myself, and I doubt the junction one would be supported by Symantec, but it might be worth a try if you're stuck and need something quick 

SMlatCST is correct in his assumption.

Here, I have moved the Users folders away from the OS drive and SEP install follows the new location of the User Profile directory.

I.E. Instead of using C:\Documents and Settings\[username], I use d:\Profiles\[username].

All of the SEP content is than moved over to the D: drive.

Hope that helps.