Have the issue on less than 0.5% of workstations (old F-S P300: Celeron 2.4 CPU, 512 Mb RAM) during upgrades from RU6 MP2 to MP3.
Killed remotely the processes COH32.exe (all where on 32-bit XP SP3):
C:\Users\username>pskill -t \\host-1089 COH32.exe
PsKill v1.13 - Terminates processes on local or remote systems
Copyright (C) 1999-2009 Mark Russinovich
Sysinternals - www.sysinternals.com
33 processes named COH32.exe killed on host-1089.
After that the setup process (msiexec.exe) CPU usage growed and it finished installing the update presumably, with the SEP-icon reappearing in the tray. Used pslist -s \\hostname for that.
That solved the problem for me.
(Now I'm calming down the users to wait for a while for the Rtvscan.exe to finish the postinstall scan, lol).