Agree with Xavier on the above, except I'd probably triple it, and you'll have to turn the min size of content to inspect down significantly for Request processing. For Response processing, the default is 4096 bytes. I usually turn that down to 2048 to inspect lower volume posts. For request processing, you're going to need that at less than 1k, so you're going to get a whole lot of traffic.
The ONLY time I've seen this scale well in a production environment was when there was significant filtering done on the ICAP service on the proxy for the Request Mod action. Without that, we estimated that where we needed only 1 Web Prevent server for Response Mod processing, we needed 3 for doing both Response and Request Mod processing.
Also, to Xavier's point, the Req Mod poses very little risk with regards to data loss, at least at a significant level. Yes, a site not coded to standard HTTP conventions can use a request to capture data, but I believe a request is limited to 1024 bytes.
~Keith