Hi soumya,
The folder you have mentioned is a quarantine folder of Trend micro Gateway antivirus....
Tren micro gateway antivirus has detected quarantined a mail containing netsky virus and it has moved these mail to that folder.
Since SEP is scanning that folder you are getting virus alerts...
Check the trend micro logs and find out from which pc these mails are getting generated. patch that pc. You can even block the sender in IMSS
Netsky is a mass mailing virus.. that is why you are getting many alerts. You can put a exception to this folder in SEP so that alerts will decrease. IMSS takes care of the files present in that folder so no need to worry..