MyCo,
SCSP is specifically designed for high-utilization servers. The IPS is not network based like in SEP, instead it uses sandboxing techniques to control the behavior of executables, and a properly tuned CSP policy will place any unknown executables into a sandbox (we call them Process Sets, or PSETs) that has limited access to the system resources or a PSET that has no access to system resources.
I have seen SEP cause network slowdown on servers when the IPS module is enabled, because it does stateful packet inspection of every packet that comes into the system, and that takes resources.
SCSP has a firewall component, but it is an application layer firewall, where we control what processes can access network connections by blocking them at the kernel level. In essence, SCSP is a gatekeeper to the kernel, and a properly tuned policy will block anything from accessing the network stack unless given permission. Because we block processes from accessing the network stack by intercepting calls to the kernel, we have an extemely low impact on network speed.
CSP also uses only between 1-5% (on the average server) of the CPU, has a very small footprint, and does not use a lot of memory.
I have seen this installed on many extremely busy domain controllers without any noticable impact on the system.