I ran into this problem and it turned out that one my disks were full. I cleared out some old backup and some old Database files. This fixed my issue. I hope this helps someone else having the same issue.
you can look into this article
Disk Space Management procedures for the SEPM
http://www.symantec.com/business/support/index?page=content&id=TECH96214
hi also remove the unwanted profile and data from Server
Also move the backup copy of Data Base on your another system.
C:\Program Files\Symantec\Symantec Endpoint Protection Manager\data\backup