Difference Encountered in File Data
Everytime a single server is backed up, there seems to be one or two files that have a "Difference Encountered in File Data" that causes the job to 'fail.' However, after the other backup jobs are run that night, the job will run again very quickly and will finish successfully. I just wanted to confirm that there wasn't much I could try, aside from cleaning the tape drive unit to see if it is possibly that that is the problem.
EDIT: Sorry, it's Backup Exec 2012. And I did see that article, but it seemed like that was for the case of it not functioning entirely. Having said that, I don't really think the single file that fails to backup is really a problem, was more looking to make sure that is the case since it almost always happens.