Thanks Brian.
I read the KB article but the error message is a bit different from the one I posted.
In my error description I can just see "250-" instead in the KB it refers to this error description
"Your email message was unable to be sent because the connection to your mail server was interrupted. Please open your email client and re-send the message from the Sent Messages folder.".
So I'm not sure it's exactly the same issue.
In any case, I was curious about option 3:
Change e-mail settings (SMTP server) to use an alternate port. (Only incoming email will be scanned.)
It would be fine for me to scan only incoming emails.
But what should I do? Should I change the account settings and enter which setting?
The SMTP port was automatically set by Outlook when it spoke to the server the first time. Which port should I enter and what would change? I think the symantec plugin would check the outlook port anyway.
Thanks again for your support!