There is an ongoing feature request for this. So, it is currently not a configuration that we recommend.
The current recommended configuration would be to use ESX/ ESXI hypervisors for virtualization.
Please see the following articles :
Feature Request: Microsoft Hyper-V Support with Symantec Encryption Management Server (previously PGP Universal Server) - http://www.symantec.com/docs/TECH175006
VMware Supported Versions - Symantec Encryption Management Server - http://www.symantec.com/docs/TECH149547