Yes there is! You need to setup an E.mail address (AD Account, Stand alone Email address) on the server that you would like the system to use.
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On page 260 of the "Administration guide" from the CD1 from Symantec:
To establish communication between Symantec Endpoint Protection Manager and email servers
1 In the console, click Admin, and then click Server.
2 Under View Servers, select the management server for which you want toestablish a connection to the email server.
3 Under Tasks, click Edit Server Properties.
4 In the Server Properties dialog box, click the Mail Server tab.
5 Type the IP address, host name, or domain name of the email server in theServer Address text box.
6 Type the user name of the account on the email server in the User Name textbox.
**You need to add a user name only if the email server requires authentication.
7 In the Server Properties dialog box, type the password of an account on theemail server in the Password text box.
**You need to add a password only if the email server requires authentication
8 Click OK.