I have read topic about Excel being slow after upgrading to RU6a, but in my case it is not just slower. If a user tries to save a file on a network share it shows saving progress and never finishes and one has to reset a computer, because it is not possible to kill Excel process (Windows Vista Business SP2). Also this sometimes happens while editing xls files on desktop. But i think these file may have links to other xls files on a share. We are using old xls format. This doesn't happen with XP machines. I have tried to uninstall SEP and install 11.0.5002.333 version on the problematic computers and so far this seems to fix the problem.
When Excel hangs in event logs there is a messages about hanging app:
0000: 006E0055 006E006B 0077006F 0000006E
0008: 0000
In Bytes
0000: 55 00 6E 00 6B 00 6E 00 U.n.k.n.
0008: 6F 00 77 00 6E 00 00 00 o.w.n...
0010: 00 00 ..
I have checked AV policies on my groups and they haven't been changed after the upgrade to RU6a. Bloodhound level is set to Default.