Hi Harshal,

We're talking about the Symantec Endpoint Protection Manager, correct?  The SEPM can interact with Exchange to distribute scheduled reports, and similar alerts, but that is the extent of the connection between the two.  There should not be any impact at all on Exchange's mail flow after installing a SEPM: it does not block any ports, etc.  It certainly does not change any Exchnage rules that would only allow internal mail to flow.

Did you reboot the server after installing the SEPM?  If so, did all services start corrected after the reboot?  Make sure that all teh necessary Exchange services are running.

Is SMSMSE also installed on this server?  There are packages/suites which provide both SEP and SMSMSE together.  Was SMSMSE just installed for the first time? 

Thanks and best regards,

Mick

Moving to SEP.

Try to stop the service of SEPM on the Exchange server and than have a look if you can send e-mail.

You have installed SEPM or SEP client on the Exchange Server.

If sep client pls go to add/remove programs -- modify -- uninstall the NTP and PTP components check

Hi Harshal,

The SEP client should detect if Exchange is installed on a server and automatically make the necessary exclusions.  There is no conflict at all between NTP or PTP components and any version of Exchange.  (Though, of course, the PTP component has limited effect on any server OS)

Please do update this thread with more information, when time allows!

Thanks and best regards,

Mick

Hi Mick,

I did rebooted the server after installing SEPM and made sure that all the exchange services are up and running fine.
Have que. regarding SMSMSE, it is not installed, is it mandatory? Does it get installed automatically installed while installing SEPM or we have to install it seperately?

Pls. suggest.

SMSMSE is not mandatory
I don't think there is any relation between SEPM and this problem.Do you have SEP client in that server.If yes try by uninstalling .NTP component of it.Also have a look at this KB
Preventing Symantec Endpoint Protection 11.0 from scanning the Microsoft Exchange 2007 directory structure

Hi Harshal,

Symantec Mail Security for MS Exchange is often sold in a suite with SEP/SEPM.  It's not manditory (though of course it is a good idea to have a security program on your Exchange server!!).

The reason that I was asking is because I can't imagine any way in which a SEPM could be responsible for what you're describing.  It doesn't interact with Exchange at all, except to distribute some alerts and notification messages.

Is the problem still happening?

Thanks and best regards,

Mick