Do you mean the client is not communicating to sepm ?
- Click the Clients tab in the SEPM and select the group you want. Right click on it and select Export Communication Settings.
- Click browse, select a convenient location and name the file "Sylink.xml".
- Click Export.
- go to client machine
- open sep client go to change settings tamper protection disable it if it is 12.1
- once done go to help troubleshooting >export communication settings and point to xml file which is exported
- once complete reboot the machine if required and check if it is reporting
for 11.0 go to start run type smc -stop
go to c:\progrfile\symantec\sep\look for sylink.xml delete it and copy the file which is exported
go to start run and type smc -start
make sure port 80 and 8014 is open on sepm machine either through windows firewall or any other firewall if you have any