Yes, you should be normally able to change the hostname of the computer when SEE-FD is installed and active. The only thing that can not be changed are the disk partitions itself:
Once Full Disk has been installed, no changes to the partition table are supported. Changes to the drive letters of encrypted disks and partitions are not supported. Before repartitioning, reformatting, resizing, or renaming any partitions on the Client Computer, you must first uninstall Full Disk.