Hi,
Supported browser with SEP 12.1 RU2
* Microsoft Internet Explorer 7, 8, 9, or 10
* Mozilla Firefox 3.6 through 15.0.1
* Google Chrome, through 22.0.1229.79
Go through this article for more details:
System Requirements for Symantec Endpoint Protection, Enterprise and Small Business Editions, and Network Access Control 12.1.2
http://www.symantec.com/docs/TECH195325