See this KB article:
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On the computer that runs Symantec Endpoint Protection Manager, on the Start menu, click All Programs > Symantec Endpoint Protection Manager > Symantec Endpoint Protection Manager Tools > Database Back Up and Restore.
In the Database Back Up and Restore dialog box, click Back Up.
In the Back Up Database dialog box, optionally check Backup logs, and then click Yes.
When the database backup completes, click Exit.
Copy the backup database file to another computer.
To back up the database and logs from within the console
In the console, click Admin, and then click Servers.
Under Servers, click the icon that represents the database.
Under Tasks, click Back Up Database Now.