There was a known issue about this - but was fixed in 12.1 RU1 so your SEPM should not be affected - for reference:
Symantec Endpoint Protection Manager 12.1 console home page showing Security Status - Attention needed
Article:TECH164272 |
| |
Created: 2011-07-10 |
| |
Updated: 2012-07-27 |
| |
Article URL http://www.symantec.com/docs/TECH164272 |
Download protection content are definitions for the download Insight protection - check if your SEPM has teh latest definitions for that - those will be classified under Reputations Settings /Definitions or Whitelist defs.
Check the same directly on few of the reported out of date clients - and compare if the revisions are the same or in fact out of date,