Hello,
In your case, Symantec is detecting such threat's as W32.Rontokbro!gen1 as Ajit pinpointed.
I agree with Mick as well for using the Symantec Power Eraser Tool.
However, in certain cases a strong Plan of Action is necessary.
Here are few Points which would assist you to prevent this.
1) Check the Host files. If they are changed make the necessary changes.
Usually Symantec does protect you from such changes, if proper policies are at place.
You can create a Application Control Policy, like to this below:
by Creating this policy, thereforth onwards all the modifications to the host file would be blocked.
2) Most of the times; such Threats are User Based. I would suggest if you could create a new user on the same machine and check if the issue exists on the new User Profile created.
If it does not exists then you can delete the Infected User Profile.
You could protect the User Profile from getting infected by creating proper policies in SEP.
How to Block Known Virus Executables that run from %UserProfile% using Application and Device Control
http://www.symantec.com/docs/TECH131741
3) Check the box for "Enable Browser Intrusion Prevention" within the Intrusion Prevention Policy of Symantec Endpoint Protection Manager which controls the user ability to enable/disable this feature.
4) Create a rule for Block / Log Browser Helper Objects.
How to create a rule that will block or log Browser Helper Objects in Symantec Endpoint Protection
http://www.symantec.com/docs/TECH94965
5) Incase, you find any suspicious files on the machines, you can follow this Article:
Using Symantec Support Tool, how do we Collect the Suspicious Files and Submit the same to Symantec Security Response Team.
Hope that helps!!