Exact version is...?
If SEP 11.x, it went end of life and you will no longer receive updates. You'll need to move to 12.1 now.
See these links for full details:
https://www-secure.symantec.com/connect/forums/symantec-endpoint-protection-110x-eosl
https://www-secure.symantec.com/connect/blogs/did-you-get-security-memo-symantec-endpoint-protection-11-eosl
Otherwise, if 12.1, run the symhelp tool to check for errors. Is there enough space on C:?