Hi,
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There are best practices articles to follow in this case.
Here it goes: Best Practices guide for moving the Symantec Endpoint Protection Manager SQL Server database from one drive to another on the same machine
http://www.symantec.com/docs/TECH106213
Best Practices guide to moving the Symantec Endpoint Protection Manager SQL Server database from an existing SQL Server database to a new SQL Server database
http://www.symantec.com/docs/TECH167300