Yes, are you running at least SEP 12.1 RU2?
If so, you can do it using the SEPM to deploy a new sylink file. See this KBA:
Restoring client-server communications with Communication Update Package Deployment
Article:HOWTO81109 |
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Created: 2012-10-24 |
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Updated: 2013-06-06 |
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Article URL http://www.symantec.com/docs/HOWTO81109 |
How many clients are you needing to do this for? If on 11.x, you can use sylink replacer.