HI,
Check this artical
How to block a user's ability to disable Symantec Endpoint Protection on Clients
http://www.symantec.com/business/support/index?page=content&id=TECH102822&locale=en_US
How to restrict users from making configuration changes to the Symantec Endpoint Protection client.
http://www.symantec.com/docs/TECH102370
also you can protect sep client service
You can Set uninstall password SEP client
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In the console, click .
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Under Clients, select the group for which you want to set up password protection.
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On the Policies tab, under Location-independent Policies and Settings, click .
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Click .
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On the Security Settings tab, choose any of the following check boxes:
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In the text box, type the password.
The password is limited to 15 characters or less.
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In the text box, type the password again.
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Click .
Check this thread
https://www-secure.symantec.com/connect/forums/notification-when-sep-client-uninstalled
https://www-secure.symantec.com/connect/forums/how-disable-disable-symantec-endpoint-protection-client-side-console