I can't find anything explicitly stating that 3TB disks have been demonstrated as working with WDE; but rather that 3TB disks not working have been confirmed as not working because of not having the default sector size. I'm not personally familar with the following from Symantec PGP Support, but it may be helpful to you:
To find out what the sector size of the
disk is, run diskprobe, then click on Drives, Physical Drives, and double-click
on PhysicalDrive1, 2 3 etc., then click "Set Active" Click OK.
Next, click on Drives again, then click Volume Information. This will tell us
the sector size of the disk.
Once you're done, click on Drives again, then click "Close Handle". Obviously,
you don't want to modify anything with this and run it as Read Only.