Pulled from Marc over at http://altirisbe.blogspot.com
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PXE-E53 error in Deployment Solution 6.8 SP2 with Initial Deploy disabled

In Deployment Solution 6.8 SP2, if Initial Deployment is disabled, the PXE client will display the error "PXE-E53 No boot filename received".

Cause

Prior to Deployment Solution 6.8 SP2, a PXE Client who is not in the Deployment Server's database would get the default PXE boot menu, using the default countdown before booting to the next device. The PXE Server in Deployment Solution 6.8 SP2 is not acting this way; instead, it does not respond to PXE Client requests if the computer is not already in the database when Initial Deploy is disabled.

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Resolution

To obtain the same reaction of a pre-6.8 SP2 PXE Server, enable Initial Deploy, set the Initial Deploy Boot Option to (None), and the timeout to the desired value.

To do this:

1. Open the Deployment Console.
2. From the Deployment Console open the PXE Configuration Utility (Tools > PXE Configuration).
3. In the PXE Configuration Utility, change to the DS tab.
4. On the DS tab, uncheck Disable Initial Deploy.
5. Change the radio button to the desired timeout option.

Also, the PXE-E53 could be a firewall change in your side. So check the firewall.

nelo

Turns out that there was no ip helper configured on the offending VLan

Thanks all