Unless you are TINY you don't want to run it all on one box. Trust me on that. I tried that in training and it failed miserably. After about 15 users it would break down due to the strain on the server. With a HUGE box you might get further, but then you will run into other fundamental bottlenecks that would bite you.
Yes, the NS will be 64bit so you could now combine that if all it does is licensing ( but if it does ANYTHING else, don't do it or you will regret it ), but i was thinking more of SD/WF/SQL since you didn't really specify.
VM support? Well that is just a company decision not to support it and not a technological reason so i don't see that changing, unless corporate philosophy changes inside Symantec.
Really, if a company cant pony up the resources to do it right, they should choose a different product or they will be disappointed. ( i know the sales guys would shoot me for saying that.. :) )