Yes, Cleanwipe will remove SMSE as well as the following -
Alert Management Server
BE
LiveUpdate
PCA
Quarantine Server
Quarantine Console
Symantec AntiVirus 9.x and 10.x
Symantec AntiVirus Corporate Edition 9.x and 10.x
Symantec Client Security 2.x and 3.x
Symantec Sygate Enterprise Protection
Symantec Protection Agent (SPA) 5.1
SEP 11 manager
SEP 11 client
Symantec Policy Manager (SPM) 5.1
Symantec Enterprise Administration (SEA) 5.1
Symantec System Center
Symantec Client Firewall
Symantec Client Firewall Administrator
Symevent