I would submit the files to Security Response to make sure they are not malicious.
http://www.symantec.com/business/security_response/submitsamples.jsp
If you suspect a false positive, submit a report here - https://submit.symantec.com/false_positive/
Once you know the files and application are good, you can create exceptions in your policy.
http://www.symantec.com/business/support/index?page=content&id=TECH91951&locale=en_US