Hi,
Try the following steps
The following steps have been shown to resolve this issue. Note that these steps assume the default installation directories for the SEPM:
1) Stop Symantec Endpoint Protection Manager Service.
2) Navigate to C:\Program Files\Symantec\Symantec Endpoint Protection Manager\db\ within Windows Explorer.
3) Locate the sem5.log and rename it to sem5.log.old
4)Open a command prompt and navigate to the following location: C:\Program Files\Symantec\Symantec Endpoint Protection Manager\ASA\win32
5)Issue the following command: dbsrv11 -f "C:\Program Files\Symantec\Symantec Endpoint Protection Manager\db\sem5.db
6) Start the Symantec Embedded Database & Manager service through the service control manager (services.msc).