HI,
It is receommended to Follow the Articles Below as per the Issue:
1) Disk Space Management procedures for the Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH96214
2) Symantec Endpoint Protection virus definition folder consumes a large amount of disk space
http://www.symantec.com/docs/TECH102927
3) Incase, you we want to Monitoring Server Health from Symantec Endpoint Protection Manager and Receive Notification, follow the Article below:
http://www.symantec.com/docs/TECH122731
Some Best Practice Articles:
1) Best Practices for configuring the number of content revisions to keep in Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH92225
2) Troubleshooting Content Delivery to the Symantec Endpoint Protection client
http://www.symantec.com/docs/TECH106034