On my Windows 10 Pro platform, since updating to 10.4.0 (Build 1100) of Symantec Encryption Desktop (uninstall/install), my acounts configured in Symantec Encryption Desktop periodically disappear. I tried going back to 10.3.2 MR 11 but was unable to do so with a complaint about failure to register a dll. I have write protected the pgppolicy.xml file but this seems like a hokey work-around. This is a standalone client and is not tied to any managed servers or policies.
The PGP log shows the following around the time of failure
<John@TheAtas.org> with subject: Test [nopgp]
IE 14:24:02 Processing message from John G. Ata <Email> with subject: Test [nopgp]
IE 14:24:09 Processing message from John Ata <Email> with subject: Test
IE 14:24:09 Creating new account list entry for 0.0.0.0 <=== Suspect this is the failure
DN 14:24:42 Policy update skipped
DN 14:24:50 Policy update skipped
DN 14:24:50 Policy update skipped
DN 14:24:50 Policy update skipped
DN 14:24:52 Policy update skipped
IE 14:25:04 Processing message from User <email>> with subject: Test
Opening up Desktop Encryption shows no accounts/policies configured - they need to be recreated.
This is easily reproducible on my system