ive got the same issue as the original poster of this message, before i used 1 NIC and wasting my almsot 2 months of configuration that even Symantec Engr don't know what to do. anyways, recently i went back the drawing board, study carefull, search everything in this SMSSMTP 5, because our company implement "branded" Symantec Security i have no choice but to pattern all security features of Symantec in my implementations/projects.
going back to SMS SMTP, i tried using 2 NIC. i have firewall appliance now here's what i did:
1. have 2 NIC, 1 is in internal network (trusted), the other 1 is in DMZ
2. internal NIC has private IP that i used for outbound email, NIC in DMZ has also private IP and is use for inbound
3. i configure both with port 25
4. i configure my Exchange 2003 Server Connectors under Routing Groups, you may use this link how to do that
http://support.microsoft.com/kb/265293 and
http://support.microsoft.com/default.aspx?scid=kb;en-us;3149615. under "Forward all mail through this connector to the following smart hosts" specify the IP of the outbound IP address in brackets like this one [192.168.1.1]
6. refresh the Exchange Server and test it.
7. as for inbound, make sure that your DMZ and Exchange meets, and make sure that you set that when SMS SMTP receives it forwards to your Exchange server which is in your trusted network
Now my outbound and inbound connection is working for me, my tears and sweat comes out before i figure it out.
Thanks to myself.