Please provide more info.
1) Exact SEP version.
2) SQL version.
Latest SEPM 12.1.5 are support below SQL version
Database
Symantec Endpoint Protection Manager includes an embedded database, and this is the only choice in Small Business Edition. In the enterprise version, you may use the embedded database or one of the following versions of Microsoft SQL Server:
- SQL Server 2005, SP4
- SQL Server 2008, through SP4
- SQL Server 2008 R2, through SP3
- SQL Server 2012, through SP1
- SQL Server 2014
http://www.symantec.com/business/support/index?page=content&id=TECH224712