Ah, I see. This definitely isn't something that we've looked at before, and neither Itanium nor clustered systems count as supported platforms for the console client, although we
do intend for the Ghost.exe component to be usable in manufacturing Itanium systems.
As for clustering, Ghost would be suited to provisioning new nodes for joining a cluster, and it could be used on an individual cluster node to take a copy of the local storage - including local quorum, if that's applicable - but imaging shared storage with it would be tricker.
The biggest issue with GSS and clusters would be that we would effectively down the node to image the storage, since we have not been given the opportunity to make Ghost work with shadow-copied volumes (and working with VSS shadow copies on shared volumes would seem to be the ideal way to image those as well). I just don't have enough experience with clusters to know whether the process you'd have to go through with Ghost manually is going to be suitable for achieving your goals.
It's certainly an interesting question - I can see the attraction in having a recovery strategy during the migration to a new edition of SQL Server. I don't think I can really give you any sensible advice as to how to use Ghost in this kind of process until I've done some background work and spent some time discussing this with my colleagues here.