Try going into Safe mode and scanning.
The Power Eraser is a good tool to use to remove these hard to find threats.
http://www.symantec.com/business/support/index?page=content&id=TECH134803&locale=en_US
The SERT is another good tool - http://www.symantec.com/business/support/index?page=content&id=TECH131732&locale=en_US
If possible submit the suspected file to Symantec or Threat Expert for analysis.
http://www.symantec.com/business/support/index?page=content&id=TECH102419&locale=en_US
http://www.threatexpert.com/submit.aspx
Moving this thread to the Endpoint forum for better visibility.
Thomas