The symptoms that are listed here are a known problem.
SEP 12.1.4 will cause problems on Windows 2012 R2 servers.
Freezing is just one of the symptoms.
On servers, the prefered option: Install SEP 12.1.7 with the AntiVirus component only, no other components.
The SEP drivers that are used for the other components are a significant source of problems on server Operating Systems (no matter what Symantec states or how much they support it - having an issue with a few dozen mission critical servers, preventing 40K users from doing their job is not what you put on your wish list while an issue is 'under investigation'...).
This will prevent a lot of issues with drive mappings disappearing, system hangups, etc.
It also pays to keep up to date with SEP version releases.
Look at the release notes what has been fixed. You might find that the problems you are experiencing are listed in those release notes.
But these are just my $ .02
Other people might have other ideas.